THE DYNAMIC CLAMP - ARTIFICIAL CONDUCTANCES IN BIOLOGICAL NEURONS

The dynamic clamp is a novel method that uses computer simulation to i ntroduce conductances into biological neurons. This method can be used to study the role of various conductances in shaping the activity of single neurons, or neurons within networks. The dynamic clamp can also be used to form circuits from previously unconnected neurons. This ap proach makes computer simulation in interactive experimental tool, and will be useful in many applications where the role of synaptic streng ths and intrinsic properties in neuronal and network dynamics is of in terest