CHROMOSOME REORGANIZATION IN CANDIDA-ALBICANS 1001-STRAIN

The karyotype of Candida albicans 1001, a pathogenic isolate, presents two additional chromosome bands when compared with C. albicans 1006 s train. These two bands were a 2600 kb chromosome located between chrom osome group 1-R and chromosome 2 (named chromosome 2) and a 710 kb sm all chromosome, called snc due to its similarity in size to the supern umerary chromosome in strain WO-1. A comparison of karyotypes of strai ns 1001, 1006 and WO-1 has enabled us to conclude that chromosomes 2 a nd 7 are involved in such a reorganization giving rise to the new chro mosome bands of strain 1001. We describe a tentative physical map of C . albicans 1001 based on the previously outlined map of C. albicans st rain 1006.