Dj. Stein et al., COMPUTED-TOMOGRAPHY AND NEUROLOGICAL SOFT SIGNS IN OBSESSIVE-COMPULSIVE DISORDER, PSYCHIATRY RESEARCH-NEUROIMAGING, 50(3), 1993, pp. 143-150
Computed tomography was used to compare the following three groups: ob
sessive-compulsive disorder (OCD) patients with high scores on a soft
neurological sign examination, OCD patients with low soft neurological
sign scores, and control subjects. Neuroanatomical structures were me
asured using quantitative volumetric analysis. OCD patients with high
soft sign scores had significantly increased ventricular volumes compa
red with OCD patients with low soft sign scores and control subjects.
Caudate and lenticular nucleus volumes did not differ between groups.