Three cases are reported of reuse of a transplanted liver graft after
early death of the first recipient due to cerebral hemorrhage. The goo
d condition of the donors; the excellent biochemical evolution of the
graft in the first recipients; total ABO compatibility and donor-recip
ient crossmatch; the absence of positivity to hepatitis B virus (HBV),
hepatitis C virus (HCV), and bacteriologic cultures; and early death
made reuse possible. The shortage of donors in relation to patients on
the waiting list and the poor clinical condition of the second recipi
ents made it necessary to adopt the decision to reuse the graft in an
attempt to save their lives. The evolution of the patients and the reu
sed grafts was satisfactory, and there were no complications that coul
d be attributed to the fact that the graft had been transplanted befor
e.