CHEMICALLY-MODIFIED PHOSPHOCITRATE AND ENTRAPMENT IN MICROPARTICLES FOR SUSTAINED INHIBITION OF BIOMINERALIZATION

Authors
SALLIS J MEEHAN J KAMPERMAN H ANDERSON M
Citation
J. Sallis et al., CHEMICALLY-MODIFIED PHOSPHOCITRATE AND ENTRAPMENT IN MICROPARTICLES FOR SUSTAINED INHIBITION OF BIOMINERALIZATION, Phosphorus, sulfur and silicon and the related elements, 76(1-4), 1993, pp. 541-544
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Phosphorus, sulfur and silicon and the related elements → ACNP
ISSN journal
10426507
Volume
76
Issue
1-4
Year of publication
1993
Pages
541 - 544
Database
ISI
SICI code
1042-6507(1993)76:1-4<541:CPAEIM>2.0.ZU;2-H
Abstract
Synthesis of glycolamide esters of phosphocitrate is described. Incorp oration of salts or modified forms of phosphocitrate into albumin/poly lactide based microspheres markedly improves efficiency in delivery. S trong inhibition of hydroxyapatite deposition into rat skin plaques wa s observed.