M. Surbled et al., TOXIC EPIDERMAL NECROLYSIS AFTER AMPICILL IN ADMINISTRATION IN A 2-YEAR-OLD CHILD, Annales francaises d'anesthesie et de reanimation, 15(7), 1996, pp. 1095-1098
The authors report a toxic epidermal necrolysis (TEN) due to ampicilli
n (Agram(R)) in a 2-year-old child. During the acute phase a septic sy
ndrome occurred. The severity of the clinical and biological symptoms
led to the administration of antibiotics, their systematic use remaini
ng controversial. Recovery was favourable in a paediatric burn centre.
Sequelae were minor. TEN, the physiopathological mechanism of which r
emaining still unknown, may carry a vital risk.