PROBING THE MECHANISM OF ACTION OF AMPHOTERICIN-B

Authors
JAMES PR RAWLINGS BJ
Citation
Pr. James et Bj. Rawlings, PROBING THE MECHANISM OF ACTION OF AMPHOTERICIN-B, Bioorganic & medicinal chemistry letters, 6(5), 1996, pp. 505-508
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
5
Year of publication
1996
Pages
505 - 508
Database
ISI
SICI code
0960-894X(1996)6:5<505:PTMOAO>2.0.ZU;2-T
Abstract
Transmembrane spanning dimers of cholesterol were unable to form ion c hannels with amphotericin B: We suggest that the two 'half pores' as p roposed by De Kruijff(1) may be aligned unsymmetrically.