C. Trumel et al., SERUM-PROTEIN ELECTROPHORESIS - GUIDELINE S FOR DIAGNOSIS EVALUATION IN THE DOG, CAT, AND HORSE, Revue de Medecine Veterinaire, 147(2), 1996, pp. 123-130
Zone electrophoresis at pH8,6 on cellulose acetate or on agarose gel i
s the most commonly used method to separate serum proteins into fracti
ons in order to study their repartition. The use of this technique is
limited as it only allows a relatively imprecise fractionation into on
ly five fractions (albumin, alpha 1-globulins, alpha 2-globulins, beta
-globulins, gamma-globulins). Thus a specific diagnosis is seldom obta
ined by this technique. But a thorough analysis of the electrophoresgr
am and the alumin/globulins ratio provides a useful screening test in
immune, renal, and hepatic disorders.