BIOTRANSFORMATION OF QUINOXALINE BY STREPTOMYCES-BADIUS

Authors
SUTHERLAND JB EVANS FE FREEMAN JP WILLIAMS AJ
Citation
Jb. Sutherland et al., BIOTRANSFORMATION OF QUINOXALINE BY STREPTOMYCES-BADIUS, Letters in applied microbiology, 22(3), 1996, pp. 199-201
Citations number
15
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Letters in applied microbiology → ACNP
ISSN journal
02668254
Volume
22
Issue
3
Year of publication
1996
Pages
199 - 201
Database
ISI
SICI code
0266-8254(1996)22:3<199:BOQBS>2.0.ZU;2-6
Abstract
Quinoxaline, a mutagenic azaarene produced in foods during cooking, wa s added to cultures of Streptomyces badius ATCC 39117. After 24 h, the cultures were extracted with ethyl acetate. Two major metabolites wer e purified by liquid chromatography and identified by mass spectrometr y and nuclear magnetic resonance spectroscopy as 3,4-dihydro-2(1H)-qui noxalinone and 2(1H)-quinoxalinone.