C. Keyl et al., A COMPARISON OF THE USE OF TRANSESOPHAGEAL DOPPLER AND THERMODILUTIONTECHNIQUES FOR CARDIAC-OUTPUT DETERMINATION, European journal of anaesthesiology, 13(2), 1996, pp. 136-142
Doppler cardiac output (GO) determination is discussed as a non-invasi
ve alternative to CO estimation by thermodilution. This study was desi
gned to compare the accuracy of a new transoesophageal Doppler device
with the thermodilution technique. In 24 patients undergoing coronary
artery bypass surgery, CO was determined simultaneously by the oesopha
geal Doppler (OD) and thermodilution (TD) method in triplicate for thr
ee sample episodes: after induction of anaesthesia during clinical ste
ady-state conditions (A), after start of surgery (B), and after sterno
tomy (C). The agreement between ODCO and TDCO estimations was assessed
by analysing the mean difference, indicating the systematic error, an
d analysing the distribution of differences between the two methods. T
he bias between ODCO and TDCO estimations was 0.38 (-0.06 to +0.81)L m
in(-1) (mean and 95% confidence interval) for sample episode A, 0.48 (
-0.11 to +1.1)L min(-1) for sample episode B, and 0.69 (+0.08 to +1.3)
L min(-1) (P<0.05 vs. zero) for sample episode C. Bias analysis of the
log-transformed data revealed that 95% of the ODCO values differed fr
om TDCO values by 43% below to 50% above for sample episode A, by 39%
below to 95% above for sample episode B, and by 32% below to 96% above
for sample episode C. Analysis of the changes in CO from sample episo
de A to B and from sample episode B to C, expressed as percentage valu
es, showed a non-significant bias between the methods, but the 2 SD li
mits were +/-44% and +/-36% respectively. Our findings suggest that CO
estimation by OD cannot replace estimation by the TD method.