EFFECT OF VARIOUS SEALERS WITH GUTTA-PERCHA AS ROOT-END FILLINGS ON HEALING AFTER REPLANTATION

This study examined histologically the effect of three sealers used wi th gutta-percha as root-end fillings placed in a replantation model. A total of 14 molar teeth were used in seven monkeys. After extraction, root ends were resected, the canals contaminated with oral bacteria, root-end cavities prepared, and fillings of gutta-percha and sealer pl aced prior to replantation. After 8 weeks the teeth and surrounding ja w were removed and prepared for histological examination. Six roots fi lled with gutta-percha plus a fortified zinc oxide-eugenol cement (IRM ) 13 with gutta-percha plus zinc oxide-eugenol (EP), and eight with gu tta-percha plus Kloropercha, were available for examination. The tissu e response to gutta-percha with either zinc oxide material was charact erized by little or no inflammation of limited extent. In contrast, mo re severe inflammation was observed against root ends filled with gutt a-percha and Kloropercha. Gutta-percha plus IRM or zinc oxide-eugenol had a much more favourable response than that to amalgam reported prev iously in a similar experiment.