The configuration space of p-tuples of pairwise distinct points in R(i
nfinity) carries a natural filtration coming from the inclusions of th
e R(n) into R(infinity). We characterize the homotopy type of this fil
tration by the combinatorial properties of an underlying cellular stru
cture and establish a close relationship to May's theory of E(n)-opera
ds. This gives a unified approach to the different known combinatorial
models of iterated loop spaces reproving by the way the approximation
theorems of Mile;ram, Smith and Kashiwabara.