L. Grondin et al., MULTIPLE INTRACEREBRAL GRANULOCYTIC SARCO MAS IN A PATIENT WITH CHRONIC MYELOID-LEUKEMIA, Canadian Association of Radiologists journal, 47(2), 1996, pp. 132-135
The authors describe a young man with known chronic myeloid leukemia w
ho sought medical attention after a first episode of seizure, The hema
tologic investigation revealed hyperleukocytosis without evidence of b
lastic transformation in peripheral blood or bone marrow, Numerous int
racerebral nodules, characterized pathologically as granulocytic sarco
mas, were demonstrated by computed tomography and magnetic resonance i
maging (MRI). The appearance of a granulocytic sarcoma in chronic myel
oid leukemia is unusual, and location of the lesion in the central ner
vous system is rare, Follow-up MRI after treatment showed almost compl
ete regression of all lesions, The radiologic features of this case ar
e discussed with reference to others reported in the literature.