Sn. Thore et al., SYNTHESIS OF SOME DIHYDROPYRIDINO TRIAZOLES AND THIADIAZOLES AND THEIR ANTIMICROBIAL ACTIVITY, Indian Journal of Heterocyclic Chemistry, 5(2), 1995, pp. 161-166
Hydrazides have been synthesized by condensing substituted dihydropyri
dine dicarboxylic acid esters with hydrazine hydrate Condensation of h
ydrazides with aryl isothiocyanates yielded thiosemicarbazides. The th
iosemicarbazides on treatment with NaOH and cone H2SO4 gave triazoles
and thiadiazoles. The synthesized compounds have been tested for their
antimicrobial activity. Some of the compounds showed significant acti
vity.