SEVERE NECROZITING VASCULITIS IN A PATIENT WITH HEPATITIS-C VIRUS-INFECTION TREATED BY INTERFERON

Authors
PATERON D FAIN O SEHONNOU J TRINCHET JC BEAUGRAND M
Citation
D. Pateron et al., SEVERE NECROZITING VASCULITIS IN A PATIENT WITH HEPATITIS-C VIRUS-INFECTION TREATED BY INTERFERON, Clinical and experimental rheumatology, 14(1), 1996, pp. 79-81
Citations number
12
Categorie Soggetti
Rheumatology
Journal title
Clinical and experimental rheumatology → ACNP
ISSN journal
0392856X
Volume
14
Issue
1
Year of publication
1996
Pages
79 - 81
Database
ISI
SICI code
0392-856X(1996)14:1<79:SNVIAP>2.0.ZU;2-Q
Abstract
We report a case of polyarteritis nodosa occurring in a patient with h epatitis C, ten days after the beginning of alpha-IFN therapy. There w as no cryoglobulinemia. Sevum HCV-RNA was detectable before INF therap y and disappeared during the vasculitits. The patient received boli of methylprednisolone and the neurological and skin lesions regressed af ter 5 months. This observation could suggest a precocious reponse to a lpha-INF and a relationship between INF and the occurrence of vasculit its.