PEPTIDE-INDUCED CHANGES IN STRUCTURE, DYNAMIC AND BARRIER PROPERTIES OF LIPOSOMES AND MEMBRANES

Authors
DUFOURCQ J DUFOURC EJ MAILLET JC CORNUT I THIAUDIERE E BONMATIN JM
Citation
J. Dufourcq et al., PEPTIDE-INDUCED CHANGES IN STRUCTURE, DYNAMIC AND BARRIER PROPERTIES OF LIPOSOMES AND MEMBRANES, Phosphorus, sulfur and silicon and the related elements, 77(1-4), 1993, pp. 665-668
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Phosphorus, sulfur and silicon and the related elements → ACNP
ISSN journal
10426507
Volume
77
Issue
1-4
Year of publication
1993
Pages
665 - 668
Database
ISI
SICI code
1042-6507(1993)77:1-4<665:PCISDA>2.0.ZU;2-M
Abstract
Peptides which have the plasma membrane as a target may induce colloid osmotic lysis of cells. This is reflected by changes in phospholipid structure and dynamics as documented by spectroscopic methods and by m odifications of their supramolecular properties such as phase stabilit y, vesicularization, fusion and micellization. From similar changes in duced both on model systems and on natural membranes, mechanisms are p roposed for biological membrane destabilization.