OCULAR MANIFESTATION OF HAIRY-CELL LEUKEMIA WITH DRAMATIC RESPONSE TO2-CHLORO-DEOXY-ADENOSINE

PURPOSE: To demonstrate that hairy cell leukemia may involve the eye. METHODS: We examined a patient who had a unique ocular manifestation o f hairy cell leukemia with severe panuveitis in one eye and leukemic r etinopathy in the fellow eye. RESULTS: Therapy with 2 chloro-deoxy-ade nosine, a drug recently introduced for treatment of hairy cell leukemi a, led to dramatic improvement of the ocular complications. CONCLUSION S: Hairy cell leukemia may involve the eye and ocular symptoms may res pond to systemic treatment with 2 chloro-deoxy-adenosine.