J. Deandres et al., A COMPARATIVE-STUDY OF ANALGESIA AFTER KNEE SURGERY WITH INTRAARTICULAR BUPIVACAINE, INTRAARTICULAR MORPHINE, AND LUMBAR PLEXUS BLOCK, Anesthesia and analgesia, 77(4), 1993, pp. 727-730
Following arthroscopic surgery of the knee, 60 ASA I-II patients were
randomly allocated to three different groups (n = 20 each) in an attem
pt to establish the best postoperative analgesic protocol: 20 ml of bu
pivacaine (0.25%; 50 mg) intraarticularly (IA) (Group 1); continuous t
hree-in-one lumbar plexus block using a catheter to administer 0.25 ml
/kg of bupivacaine (0.25%; single-shot) plus continuous pump infusion
of the same drug (0.03 ml.kg-1.h-1 of 0.25% bupivacaine for 24 h) (Gro
up 2); or 1 mg of morphine with 20 ml of saline IA (Group 3). The resu
lts were appraised in a double-blind manner, and the degree of postope
rative pain was evaluated by visual analog scale (VAS) at constant hou
rly intervals for the first 24 h, by the incidence of secondary effect
s, and by the need for complementary analgesia. Group 2 (three-in-one)
VAS values were lower 16 and 24 h after surgery and also globally (P
< 0.05), with respect to the other two groups. Five patients in Groups
1 and 3 required complementary analgesia, while three patients in Gro
up 1 suffered nausea. No other secondary effects were observed. We con
clude that all three analgesic methods proved efficient, as reflected
by the scant requirements for additional analgesics and the degree of
expressed patient satisfaction. However, lumbar plexus block (three-in
-one) with continuous bupivacaine infusion was most effective, and, al
though it constitutes an added technique, its scant complications and
easy performance make its use advisable.