KIM127, AN ANTIBODY THAT PROMOTES ADHESION, MAPS TO A REGION OF CD18 THAT INCLUDES CYSTEINE-RICH REPEATS

Authors
STEPHENS P ROMER JT SPITALI M SHOCK A ORTLEPP S FIGDOR CG ROBINSON MK
Citation
P. Stephens et al., KIM127, AN ANTIBODY THAT PROMOTES ADHESION, MAPS TO A REGION OF CD18 THAT INCLUDES CYSTEINE-RICH REPEATS, Cell adhesion and communication, 3(5), 1995, pp. 375-384
Citations number
34
Categorie Soggetti
Cell Biology",Biology
Journal title
Cell adhesion and communication → ACNP
ISSN journal
10615385
Volume
3
Issue
5
Year of publication
1995
Pages
375 - 384
Database
ISI
SICI code
1061-5385(1995)3:5<375:KAATPA>2.0.ZU;2-L
Abstract
A series of fusion proteins have been generated between human and mous e CD18. These proteins have been used to carry out preliminary mapping studies on a number of anti-CD18 antibodies including KIM127 an antib ody that promotes CD18-dependent adhesion. This antibody maps to a reg ion of the CD18 molecule between amino acids 406 and 570 in a region c ontaining cysteine-rich repeats.