During a four year period, 50 patients were evaluated for possible tho
racic outlet syndrome (TOS), These 11 men and 39 women ranged in age f
rom 27 to 60 years, with a mean age of 38.6 years. Their symptoms had
been present from 3 months to 10 years (mean = 2.1 years). Twenty-seve
n had previously undergone 33 operations, including carpal funnel rele
ase, shoulder arthroscopy, rotator cuff repair, cervical discectomy, a
nd first rib resection, all without benefit. Patients were evaluated b
y history, physical examination, and radiographs of the cervical spine
and chest. Additional studies such as electromyography/nerve conducti
on studies, computed tomography, magnetic resonance imaging, angiograp
hy, and myelography were obtained selectively. Only 12 patients were t
hought to have TOS, seven of whom underwent operation. Four had comple
te resolution of symptoms; three were improved but had residual sympto
ms for associated problems. Three patients who were not thought to hav
e TOS underwent first rib resection in other hospitals; none was impro
ved after surgery. The only study of positive value was evidence of un
ilateral subclavian artery compression with shoulder positioning on ph
ysical examination. All other studies were of value only if they demon
strated some other cause of the patient's symptoms. Of the 35 patients
without TOS in whom long-term follow-up was obtained, four underwent
appropriate operations with benefit, and 20 had good results from phys
ical therapy and nonoperative management. Patients whose symptoms were
work-related, and those who had engaged the services of a lawyer, wer
e less likely to demonstrate improvement, regardless of the treatment
employed. TOS is a relatively unusual cause of upper extremity pain an
d dysfunction. History and physical examination are the most important
diagnostic studies, and radiographs of the chest and cervical spine a
nd electromyography/nerve conduction studies are useful to identify ot
her causes of pain and disability. Careful selection of patients for s
urgery can yield satisfactory results. A coordinated team of surgeons,
neurologists, and physical therapists is important in the management
of these patients.