Rhabdomyolysis can be precipitated by trauma, ischemia, metabolic defe
cts, electrolyte abnormalities, drugs, and a wide variety of infectiou
s diseases. At our institution, recent cases of rhabdomyolysis induced
by influenza prompted us to review the infectious etiologies of this
entity. In addition, a thorough literature search revealed numerous ca
se reports but no general review on this subject. This study describes
representative recent cases from our institution and details the wide
variety of infections that can cause muscle damage. The pathophysiolo
gical mechanisms, muscle histology, and correlation with renal dysfunc
tion are also discussed.