Bt. Cho et Ys. Chun, ENANTIOSELECTIVE SYNTHESIS OF OPTICALLY-ACTIVE METOLACHLOR VIA ASYMMETRIC REDUCTION, Tetrahedron : asymmetry, 3(3), 1992, pp. 337-340
Optically active metolachlor was prepared by chloroacetylation of the
corresponding amine obtained by asymmetric reduction of the requisite
imine with the chiral hydrides, such as Itsuno's reagent (4), Corey's
reagent (5) and K glucoride (6).