ENANTIOSELECTIVE SYNTHESIS OF 4 ISOMERIC BUILDING-BLOCKS USEFUL IN THE SYNTHESIS OF 2-NOR-LEUKOTRIENE ANALOGS

Authors
BELLAMY FD BONDOUX M BOUBIA B DODEY P MIOSKOWSKI C
Citation
Fd. Bellamy et al., ENANTIOSELECTIVE SYNTHESIS OF 4 ISOMERIC BUILDING-BLOCKS USEFUL IN THE SYNTHESIS OF 2-NOR-LEUKOTRIENE ANALOGS, Tetrahedron : asymmetry, 3(3), 1992, pp. 355-358
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
3
Issue
3
Year of publication
1992
Pages
355 - 358
Database
ISI
SICI code
0957-4166(1992)3:3<355:ESO4IB>2.0.ZU;2-9
Abstract
We report, in this letter, the enantioselective synthesis of four isom eric functionalized epoxides (3a, 3b, 3c and 3d) which are useful buil ding blocks for the synthesis of 2-nor-leukotriene analogues. All four epoxides are formally derived from a single non chiral starting mater ial, the 2-butyne-1,4-diol 7.