R. Landymore et al., RANDOMIZED TRIAL COMPARING INTERMITTENT ANTEGRADE WARM BLOOD CARDIOPLEGIA WITH MULTIDOSE COLD BLOOD CARDIOPLEGIA FOR CORONARY-ARTERY BYPASS, European journal of cardio-thoracic surgery, 10(3), 1996, pp. 179-184
Forty patients were randomized to receive antegrade multidose warm (WB
C) or cold blood cardioplegia (CBC) during coronary artery bypass. Car
dioplegia was infused at a predetermined dose every 10 min during card
ioplegia arrest and core temperature was maintained at 37 degrees C in
both groups during extracorporeal circulation. Patient profiles were s
imilar in the two groups. Cardiac index, left ventricular stroke work
index, and myocardial oxygen consumption were measured beforebypass an
d during the first 7 h of reperfusion. There was no significant differ
ence in myocardial metabolic and function recovery, the incidence of m
yocardial infarction, low cardiac output or death. Our data suggests t
hat similar protection is provided with the two techniques of myocardi
al protection.