Thermally stimulated current spectroscopy has been applied to the inve
stigation of molecular mobility in human calcified tissue. A comparati
ve study of extracts and residues at various stages of demineralizatio
n is presented. Results show that: the matrix (collagen) is in a glass
y state at physiological temperature; the filler (apatite) increases t
he static modulus; the interfaces/interphase (non-collagenous proteins
and particularly proteoglycans) ensure cohesion and ductability for t
he composite. Biomaterials for orthopaedic prostheses require the same
morphology in order to phenomenologically reproduce the same dynamic
behaviour.