INCREASED NUMBERS OF INTERLEUKIN-12-PRODUCING CELLS IN HUMAN TUBERCULOSIS

Authors
MUNK ME MAYER P ANDING P FELDMANN K KAUFMANN SHE
Citation
Me. Munk et al., INCREASED NUMBERS OF INTERLEUKIN-12-PRODUCING CELLS IN HUMAN TUBERCULOSIS, Infection and immunity, 64(3), 1996, pp. 1078-1080
Citations number
14
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
64
Issue
3
Year of publication
1996
Pages
1078 - 1080
Database
ISI
SICI code
0019-9567(1996)64:3<1078:INOICI>2.0.ZU;2-Z
Abstract
Numbers of interleukin-12 (IL-12)-producing cells were quantitated in the peripheral blood of healthy donors and tuberculosis patients by th e ELISPOT assay. We observed that (i) stimulation with mycobacteria in creases numbers of IL-12 producers from healthy donors and (ii) tuberc ulosis patients have larger numbers of IL-12 producers than healthy do nors. Our data emphasize the importance of IL-12 in immunity to tuberc ulosis.