Us. Pathak et al., SYNTHESIS OF SOME 4]TRIAZOLO[4,3-A]THIENO[3,2-E]PYRIMIDIN-5(4H)-ONES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 31(4), 1992, pp. 223-229
A series of hitherto unreported 4]triazolo[4,3-a]thieno[3,2-e]pyrimidi
n-5(4H)-ones (8a-k) have been synthesized by the condensation of ydraz
ino-3-phenylthieno[2,3-d]pyrimidin-4(3H)-ones (7a,b) with various one-
carbon donors. Compounds, 8c and 8g, exhibit significant CNS depressan
t and analgesic activities, respectively.