IMMUNE REGULATION - A CRITICAL LINK BETWEEN NK CELLS AND CTLS

Authors
KOS FJ ENGLEMAN EG
Citation
Fj. Kos et Eg. Engleman, IMMUNE REGULATION - A CRITICAL LINK BETWEEN NK CELLS AND CTLS, Immunology today, 17(4), 1996, pp. 174-176
Citations number
31
Categorie Soggetti
Immunology
Journal title
Immunology today → ACNP
ISSN journal
01675699
Volume
17
Issue
4
Year of publication
1996
Pages
174 - 176
Database
ISI
SICI code
0167-5699(1996)17:4<174:IR-ACL>2.0.ZU;2-D
Abstract
An immune response to pathogen typically involves progression from inn ate immunity to adaptive immunity. The questions of whether and how in nate immunity influences adaptive immunity and vice versa are still la rgely unexplored. Here, Ferdynand Kos and Edgar Engleman propose that natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) regulate the functions of each other, thereby controlling the outcome of an imm une response.