GENETICALLY DIVERSE PIG MODELS FOR NEONATAL CHOLESTEROL NUTRITION - AREVIEW

Lipid metabolism and cholesterol homeostasis in swine are reviewed in relation to the use of the pig as a model for studying nconatal choles terol nutrition. Several genetically unique pig populations used in ca rdiovascular and obesity research are described. Recent work with two specific genetically selected dietary cholesterol during the neonatal period modulates central nervous system development and atherogenesis in some genetically distinct populations of swine. Implications for th e role of dietary cholesterol in human infant nutrition are discussed.