We report a patient with extramedullary acute promyelocytic leukemia (
APL) occurring after radiation therapy for carcinoma of the prostate.
To the authors' knowledge, this patient represents the first case of c
ytogenetically and fluorescence in situ hybridization (FISH) confirmed
therapy-related extramedullary APL. In contrast to the majority of pr
eviously reported t-APL, this case underwent a very unfavorable course
.