Cytogenetic analysis of a unicameral bone cyst surgically resected in
an 11-year-old boy revealed a highly complex clonal structural rearran
gement involving chromosomes 4, 6, 8, 16, 21, and both 12. These findi
ngs reinforce the need for further studies on unicameral bone cysts to
verify the frequency and to understand the significance of chromosome
anomalies in this type of lesion.