OLFACTORY RECEPTOR-ENCODING GENES AND PSEUDOGENES ARE EXPRESSED IN HUMANS

Authors
CROWE ML PERRY BN CONNERTON IF
Citation
Ml. Crowe et al., OLFACTORY RECEPTOR-ENCODING GENES AND PSEUDOGENES ARE EXPRESSED IN HUMANS, Gene, 169(2), 1996, pp. 247-249
Citations number
10
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
169
Issue
2
Year of publication
1996
Pages
247 - 249
Database
ISI
SICI code
0378-1119(1996)169:2<247:ORGAPA>2.0.ZU;2-Y
Abstract
A putative olfactory receptor-encoding gene was cloned from human geno mic DNA and shown to be expressed by isolation of a full-length cDNA f rom olfactory tissue. A second cDNA clone was found to encode an olfac tory receptor pseudogene. The expression of a pseudogene from the olfa ctory gene repertoire, in neurons which express only a single receptor type, implies that many neurons will be non-functional.