CLONING OF A CDNA-ENCODING A MOUSE TRANSCRIPTIONAL REPRESSOR DISPLAYING STRIKING SEQUENCE CONSERVATION ACROSS VERTEBRATES

Authors
GENETTA T KADESCH T
Citation
T. Genetta et T. Kadesch, CLONING OF A CDNA-ENCODING A MOUSE TRANSCRIPTIONAL REPRESSOR DISPLAYING STRIKING SEQUENCE CONSERVATION ACROSS VERTEBRATES, Gene, 169(2), 1996, pp. 289-290
Citations number
13
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
169
Issue
2
Year of publication
1996
Pages
289 - 290
Database
ISI
SICI code
0378-1119(1996)169:2<289:COACAM>2.0.ZU;2-K
Abstract
The nucleotide sequence encoding an approx. 120-kDa transcriptional re pressor (MEB1) was determined from a cDNA which was cloned from a mous e brain library. An alignment of the deduced amino-acid sequences of t he putative functional domains of MEB1 with those from the human, hams ter and chicken homologues reveals a dramatic degree of conservation.