T. Genetta et T. Kadesch, CLONING OF A CDNA-ENCODING A MOUSE TRANSCRIPTIONAL REPRESSOR DISPLAYING STRIKING SEQUENCE CONSERVATION ACROSS VERTEBRATES, Gene, 169(2), 1996, pp. 289-290
The nucleotide sequence encoding an approx. 120-kDa transcriptional re
pressor (MEB1) was determined from a cDNA which was cloned from a mous
e brain library. An alignment of the deduced amino-acid sequences of t
he putative functional domains of MEB1 with those from the human, hams
ter and chicken homologues reveals a dramatic degree of conservation.