N. Harata et Y. Iwasaki, THE BLOOD-BRAIN-BARRIER AND SELECTIVE VULNERABILITY IN EXPERIMENTAL THIAMINE-DEFICIENCY ENCEPHALOPATHY IN THE MOUSE, Metabolic brain disease, 11(1), 1996, pp. 55-69
The integrity of the blood-brain barrier (BBB) is an important aspect
of normal central nervous system (CNS) function. Recently, it was show
n that the BBB breakdown is one of the predisposing factors in the pat
hogenesis or thiamine-deficiency encephalopathy. The result is discuss
ed along with some reviews on previous research of BBB integrity in th
iamine deficiency.