Ar. Samadi et al., MATERNAL HYPERTENSION AND ASSOCIATED PREGNANCY COMPLICATIONS AMONG AFRICAN-AMERICAN AND OTHER WOMEN IN THE UNITED-STATES, Obstetrics and gynecology, 87(4), 1996, pp. 557-563
Objective: To characterize maternal hypertension and related pregnancy
complications among African-American and other women in the United St
ates. Methods: Using data from the National Hospital Discharge Survey,
we analyzed the incidence and clinical spectrum of maternal hypertens
ion among African-American women who delivered in hospital during 1988
-1992. Maternal hypertension consisted of: pregnancy-induced hypertens
ion and chronic hypertension preceding pregnancy, including pregnancy-
aggravated hypertension. Pregnancy-induced hypertension included preec
lampsia, eclampsia, and transient hypertension. Incidence rates (per 1
000 deliveries) and 95% confidence intervals (CI) were calculated by t
ype of hypertension and demographic characteristics. Risk ratios and 9
5% CIs for adverse pregnancy outcomes among women with hypertension we
re also calculated. Results: The overall incidence of all causes of ma
ternal hypertension was 64.2, and of chronic hypertension preceding pr
egnancy it was 25.0 per 1000 deliveries among African-American women,
an excess of 15.6 and 14.5 cases per 1000 deliveries, respectively, co
mpared with rates for other women. The risks of preterm delivery and i
nadequate fetal growth were similarly increased for all hypertensive w
omen, regardless of race. However, hypertensive African-American women
were at a threefold greater risk of pregnancies complicated by antepa
rtum hemorrhage, an association that was not observed in other women.
Development of preeclampsia and eclampsia irrespective of race was abo
ut four times higher among women with chronic hypertension preceding p
regnancy than among those without chronic hypertension. Conclusion: Th
e excess incidence of maternal hypertension, particularly chronic hype
rtension, may contribute to adverse maternal and fetal pregnancy outco
mes and the disparity in outcomes observed between African-American an
d other women in the U.S. These findings provide a specific focus for
further clinical outcomes research and assessment of prenatal manageme
nt in African-American women.