Objective: To determine if there is an association between the degree
of thoracic kyphosis and the prevalence of advanced uterine prolapse i
n women. Methods: A retrospective case-control study compared the degr
ee of thoracic kyphosis among white women with advanced uterine prolap
se with that of matched controls. Medical records were reviewed for 41
2 consecutive women who underwent either abdominal or vaginal hysterec
tomy. The cases were those with uterine prolapse to or beyond the leve
l of the introitus, and women with no evidence of prolapse served as c
ontrols. Spinal curvature was measured preoperatively for each patient
using a lateral chest x-ray and the Ferguson method. Forty-eight case
s were matched to 48 controls for age, weight, menopausal status, and
hormonal status. Results were stratified to analyze the effect of pari
ty on the relationship between uterine prolapse and thoracic kyphosis.
Results: The degree of thoracic kyphosis was higher in patients with
uterine prolapse than in controls (mean paired difference = 4.9 degree
s, 95% confidence interval [CI] 3.1-6.7; P < .001). Patients with uter
ine prolapse had a mean spinal curvature of 13.0 degrees (95% CI 11.5-
14.5), whereas controls had one of 8.1 degrees (95% CI 6.9-9.4). A hig
her degree of thoracic kyphosis was associated with an incremental hig
her occurrence of uterine prolapse (odds ratio 1.35, 95% CI 1.11-1.65;
P < .01). Conclusion: Thoracic kyphosis appears to be associated with
uterine prolapse.