Jc. Girling et Wp. Soutter, CYTOREDUCTIVE SURGERY IN THE PRIMARY MANAGEMENT OF ADVANCED EPITHELIAL OVARIAN-CARCINOMA - A TOPIC FOR DEBATE, International journal of gynecological cancer, 6(2), 1996, pp. 81-84
While there is no doubt that surgical resection of early stage ovarian
cancer can be curative, the effect of cytoreductive surgery on the pr
ognosis in advanced disease is less certain. A recent EORTC study does
suggest that intervention debulking surgery might improve survival an
d this requires urgent confirmation. Extensive cytoreductive surgery,
removing bowel, parts of the urinary tract or lymph nodes, may have li
ttle impact on the survival of women with advanced disease and can res
ult in substantial morbidity. Discretion and experience are required i
n determining the appropriate radicality of tumor resection to avoid p
redictable impairment of quality of life.