A FAST METHOD FOR IN-VIVO LACTATE IMAGING

A robust method for fast lactate imaging is presented using a combinat ion of a lactate editing sequence and a one-shot imaging experiment. T he lactate editing method is based on manipulation of the phase of the lactate CH3 signal via J-modulation. This is applied as a preparation experiment to the U-FLARE imaging sequence, Phantom experiments are p resented in which the quality of water and lipid suppression is establ ished. Edited lactate images with a spatial resolution of 3 mu L and t otal measuring time of 15.8 min are shown, These were obtained from a hemispherical ischemia in the gerbil brain, The images are compared wi th diffusion-weighted water images.