CYTOGENETIC SUPPORT FOR PRIMACY PROSTATIC-CANCER IN A PATIENT PRESENTING WITH A SOFT-TISSUE MASS IN THE LEG

A 65-year-old man presented with a soft tissue mass in the leg, clinic ally suspect of a sarcoma. Histologic examination suggested a metastat ic adenocarcinoma of the prostate, which could not be confirmed by imm unohistologic studies. However, cytogenetic analysis strongly supporte d this diagnosis. A primary prostatic carcinoma was indeed found and t he patient died of widely disseminated disease. These findings illustr ate the significance of chromosomal analysis in the search for a prima ry tumor in patients with an unknown primary.