DETERMINATION OF THE NEUROTRANSMITTER IN THE BRAIN USING COMPOSITE - POLYMER MICROELECTRODES

Citation
Tz. Peng et al., DETERMINATION OF THE NEUROTRANSMITTER IN THE BRAIN USING COMPOSITE - POLYMER MICROELECTRODES, Gaodeng xuexiao huaxue xuebao, 16(12), 1995, pp. 1847-1851
Citations number
11
Categorie Soggetti
Chemistry
ISSN journal
02510790
Volume
16
Issue
12
Year of publication
1995
Pages
1847 - 1851
Database
ISI
SICI code
0251-0790(1995)16:12<1847:DOTNIT>2.0.ZU;2-#
Abstract
A composite polymer carbon fiber electrode modified with Nafion and ce llulose acetate is described, The incorporation of ion exchanging poly mer to the cellulose acetate domain allows the binding of counterionic reactants, while maintaining the size exclusion discriminative proper ties of cellulose acetate. In vivo voltammetry, the modified microelec trode inhabits the oxidation of some neurotransmitter metabolites and electroactive compounds, such as DOPAC, 5-HIAA, HVA, AA and UA; and su ccessfully detects the oxidative current of neurotransmitter DA.