INSULIN, GROWTH-FACTORS, AND CAMP - ANTAGONISM IN THE SIGNAL-TRANSDUCTION PATHWAYS

Authors
GRAVES LM LAWRENCE JC
Citation
Lm. Graves et Jc. Lawrence, INSULIN, GROWTH-FACTORS, AND CAMP - ANTAGONISM IN THE SIGNAL-TRANSDUCTION PATHWAYS, Trends in endocrinology and metabolism, 7(2), 1996, pp. 43-50
Citations number
76
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Trends in endocrinology and metabolism → ACNP
ISSN journal
10432760
Volume
7
Issue
2
Year of publication
1996
Pages
43 - 50
Database
ISI
SICI code
1043-2760(1996)7:2<43:IGAC-A>2.0.ZU;2-0
Abstract
Depending on the cell type and the response, cAMP may either oppose or facilitate the actions of insulin and/or growth factors that signal v ia receptor tyrosine kinases. Recent findings indicate that the effect s of the cyclic nucleotide are mediated in part by changes in the acti vities of important elements in the signal transduction path ways util ized by insulin and growth factors.