Jv. Villasin et al., MANAGEMENT OF SKIN TEARS AND STAGE-II SKIN ULCERS WITH 2 TOPICAL REGIMENS - A STUDY OF COST MINIMIZATION, Advances in therapy, 13(1), 1996, pp. 10-19
Citations number
18
Categorie Soggetti
Medicine, Research & Experimental","Pharmacology & Pharmacy
A health-economic study of newly formed skin tears and stage II ulcers
used an unblinded, comparative, parallel-group design to evaluate two
topical regimens as to time required for complete healing and assessm
ent of cost minimization. Thirty-six elderly patients, at risk for dev
eloping indolent wounds of the skin and underlying tissues, were assig
ned to receive either a saline spray and a topical antibiotic ointment
(TAM, n = 14) or Dermagran(R) Spray and Dermagran(R) Ointment (DSO, n
= 22). The 76 wounds that appeared in these patients had comparable p
retreatment surface areas of 3.73 +/- 0.96 cm(2) in the DSO group vers
us 5.57 +/- 1.13 cm(2) in the TAM group (P = NS). All wounds were trea
ted twice daily, starting within 24 hours of their appearance, until c
omplete healing. The 19 wounds in the TAM group healed within 48.0 +/-
25.3 days versus 15.4 +/- 1.9 days for the 57 wounds in the DSO group
(P<.05). The cost of wound management for a given patient was calcula
ted by adding the costs of nursing labor and the amount of product con
sumed to effect complete healing. To this end, the cost of the TAM reg
imen was $323.23 +/- 171.70 versus $104.75 +/- 12.92 for the DSO regim
en (P<.05). Results are presented in light of the increasing pressure
on long-term care facilities to provide effective and affordable treat
ment.