ELEMENTS OF IMMUNITY - THE INSTRUCTIVE ROLE OF INNATE IMMUNITY IN THEACQUIRED IMMUNE-RESPONSE

Authors
FEARON DT LOCKSLEY RM
Citation
Dt. Fearon et Rm. Locksley, ELEMENTS OF IMMUNITY - THE INSTRUCTIVE ROLE OF INNATE IMMUNITY IN THEACQUIRED IMMUNE-RESPONSE, Science, 272(5258), 1996, pp. 50-54
Citations number
85
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Science → ACNP
ISSN journal
00368075
Volume
272
Issue
5258
Year of publication
1996
Pages
50 - 54
Database
ISI
SICI code
0036-8075(1996)272:5258<50:EOI-TI>2.0.ZU;2-7
Abstract
Innate immunity has been considered only to provide rapid, incomplete antimicrobial host defense until the slower, more definitive acquired immune response develops. However, innate immunity may have an additio nal role in determining which antigens the acquired immune system resp onds to and the nature of that response. Knowledge of the molecules an d pathways involved may create new therapeutic options for infectious and autoimmune diseases.