ENANTIOSELECTIVE GAS-CHROMATOGRAPHY

Gas chromatography (GC) is an attractive alternative for the direct se paration of volatile and thermally stabile enantiomers. In addition to the high efficiency and the ''universal'' and sensitive detection GC also offers an unique advantage, i.e., a possibility to separate enant iomers that can interact with the chiral stationary phase (CSP) via va n der Waals' forces only. In this article the state of the art is revi ewed with special emphasis on cyclodextrin based CSPs. In addition, th e applicability as well as the choice of chiral stationary phases are addressed. (C) 1996 John Wiley & Sons, Inc.