A NOVEL SULFATE POLYMER AS A PSEUDO-STATIONARY PHASE FOR MICELLAR ELECTROKINETIC CHROMATOGRAPHY

A stable monomolecular pseudo-stationary phase for use in micellar ele ctrokinetic chromatography has been synthesized and evaluated. Sodium 10-undecenyl sulfate has been synthesized and polymerized to form a mi celle-like structure following a procedure similar to that previously employed for sodium 10-undecylenate. As with other high molecular surf actants, the effective critical micelle concentration of this pseudo-s tationary phase is zero. Covalent stabilization of the micelle does no t adversely affect the efficiency of the separations. The new phase ha s higher electrophoretic mobility than micelles of sodium dodecyl sulf ate, thus providing a wider elution range. The stability of the new ph ase permits its use with relatively high percentages of organic modifi ers in the mobile phase, allowing the separation of hydrophobic solute s. (C) 1996 John Wiley & Sons, Inc.