Purpose: To evaluate the effect of radiation dose reduction on image q
uality in computed musculoskeletal radiography and determine optimal e
xposure range. Material and Methods: In 11 corpses. 1 hand and 1 hip w
ere examined with film-screen radiography, and a series of computed ra
diographs was obtained using exactly the same technique except for the
exposure, which was 100, 50, 25, 12.5, 6.25, and 1.56% of the mAs num
bers used for the film-screen images. The computed hip radiographs wer
e processed in 2 different ways, one simulating the film-screen images
and one using contrast enhancement. Four radiologists reviewed the im
ages regarding the following parameters: cortical bone, trabecular bon
e, joint space. and soft tissue, giving each a diagnostic quality rati
ng on a scale from 1 to 5. The median and mean values were found for t
he pooled results. Results: For the hands, the computed radiographs we
re ranked inferior to the film-screen images for all parameters except
soft tissue, where the computed radiographs scored higher. The comput
ed images with 50 and 25% exposure were ranked equal to the 100% ones.
The quality rating slowly declined with lower exposures. For the hips
, the 100 and 50% computed radiographs were generally similar to or sl
ightly better than the film-screen images. The decline was somewhat fa
ster than for the hands. The contrast-enhanced hip images scored less
than the nonenhanced images at any given exposure for all parameters e
xcept soft tissue, where the contrast-enhanced images scored better at
all exposures. The difference between nonenhanced and enhanced images
became less at the lower exposures. Conclusion: Lowering the exposure
in computed musculoskeletal radiography below the level of film-scree
n radiography is feasible, especially in the peripheral skeleton. Cont
rast enhancement seems to be valuable only in the evaluation of soft-t
issue structures.