Brachmann-de Lange syndrome (BDLS) is a well-delineated and relatively
common syndrome. However, prenatal diagnosis has never been reported,
even if in some cases ultrasonography demonstrated one or more manife
stations of the syndrome. We report on 3 cases: in the first 2 cases,
prenatal ultrasonography demonstrated some signs of the condition. The
third represents, to our knowledge, the first prenatal diagnosis of B
DLS. We also present a review of the literature concerning pre- and po
stnatal findings in this syndrome. (C) 1996 Wiley-Liss, Inc.