The biological transmissibility of buffalopox virus (BPV) was studied
in a number of different animal species. Animal infectivity experiment
s revealed a wide biological host-range for buffalopox virus which was
transmissible experimentally to buffaloes, cows, rabbits, guinea-pigs
and suckling mice (BALB/C and Swiss-white mice strains). Sheep, goat,
fowl and adult mice (BALB/C and Swiss-white strains) were found refra
ctory to buffalopox: infection. Experimental transmission is being rep
orted for the first time in cow-calves and BALB/C mice.