ORGANO CERIUM REAGENTS IN ORGANIC-CHEMISTRY - GENERAL-METHOD OF SYNTHESIS OF ALKYL SUBSTITUTED 1,3-DIOLS BY RLI-CECL3 ADDITION TO BETA-HYDROXYKETONES

Authors
BARTOLI G BOSCO M VANBEEK J SAMBRI L MARCANTONI E
Citation
G. Bartoli et al., ORGANO CERIUM REAGENTS IN ORGANIC-CHEMISTRY - GENERAL-METHOD OF SYNTHESIS OF ALKYL SUBSTITUTED 1,3-DIOLS BY RLI-CECL3 ADDITION TO BETA-HYDROXYKETONES, Tetrahedron letters, 37(13), 1996, pp. 2293-2296
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
13
Year of publication
1996
Pages
2293 - 2296
Database
ISI
SICI code
0040-4039(1996)37:13<2293:OCRIO->2.0.ZU;2-7
Abstract
Organocerium compounds (RLi-CeCl3) are able to transfer an alkyl group to the carbonylic function of a beta-hydroxyketone giving alkyl subst ituted 1,3-diols in excellent yields. The use of these not sophisticat ed reagents is essential to depress undesired dimetallation and retroa ldol side processes.