N-ALKYLATION OF AMINO-ACID ESTERS USING SODIUM TRIACETOXYBOROHYDRIDE

Authors
RAMANJULU JM JOULLIE MM
Citation
Jm. Ramanjulu et Mm. Joullie, N-ALKYLATION OF AMINO-ACID ESTERS USING SODIUM TRIACETOXYBOROHYDRIDE, Synthetic communications, 26(7), 1996, pp. 1379-1384
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
26
Issue
7
Year of publication
1996
Pages
1379 - 1384
Database
ISI
SICI code
0039-7911(1996)26:7<1379:NOAEUS>2.0.ZU;2-V
Abstract
N-Alkylation of amino acid esters by reductive amination using sodium cyanoborohydride may often be problematic. Sodium triacetoxyborohydrid e was found to be a convenient reagent for this transformation. This m ethodology was employed to alkylate various amino acid methyl esters.